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Everyone makes GLP-1 when they eat

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They do a lot: regulate insulin secretion stimulate the gallbladder to release bile help with digestion and nutrient absorption keep food moving through and out of the body (known as gut motility) help regulate appetite and satiety (fullness) Some gut peptides you may have heard of: glucagon-like peptide 1 (GLP-1) glucose-dependent insulinotropic polypeptide (GIP) ghrelin (the hunger hormone) Gut peptides like GLP-1 and GIP lower blood sugar levels, which is also known as the incretin effect

Sources Eli Lilly press release: Lilly's triple agonist, retatrutide, successful in two additional Phase 3 obesity trials, delivering significant improvements in weight and A1C