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Black tea polyphenol Theaflavin as promising antioxidant and potential copper chelator
The insulin receptor changes conformation in unforeseen ways on ligand binding: sharpening the picture of insulin receptor activation
Collectively they belong to a class of glucagon-like peptide 1 (GLP-1) analogs that has reshaped the treatment of obesity and diabetes so thoroughly that the word blockbuster barely covers it
Lexchin J et al
The SUMMIT trial took this further with tirzepatide, showing a 38% reduction in the composite of cardiovascular death or worsening heart failure (HR 0.62) in patients with HFpEF and obesity, along with a clinically meaningful 6.9-point improvement in KCCQ scores
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