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This weighting dropped the crude hazard ratios of 2.08 and 1.60 to 1.02 and 0.91 in the comparisons with DPP-4 inhibitors and SGLT-2 inhibitors, respectively

For international markets like Australia, the UK, and Canada, add another 12 to 24 months after US approval

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General Eligibility Criteria: Based on published clinical guidelines, GLP-1 medications for weight management are typically considered for adults with BMI of 30 or higher, or BMI of 27 or higher with at least one weight-related condition such as hypertension, hyperlipidemia, type 2 diabetes, or pre-diabetes