While no proven treatments exist yet, some investigational approaches include N-Acetylcysteine (NAC), an antioxidant that may help reduce neuroinflammation, Low-Dose Naltrexone (LDN), a medication being studied for its effects on immune function and brain fog, and Modafinil (Provigil), which is sometimes used to counteract fatigue-related cognitive dysfunction
Similar versions of both semaglutide (brand name Ozempic) and tirzepatide (brand name Mounjaro) are approved for type 2 diabetes mellitus
For women with lipoedema who already commonly present with digestive issues, histamine intolerance, MCAS, reflux associated with hiatus hernia, or who wear compression garments that fit around the abdomen, which can place upward pressure on the stomach, this cascade of gastrointestinal complications is a very real and underacknowledged risk that needs consideration before starting these medications
Aggressive marketing has pushed this further
Rodbard HW, Rosenstock J, Canani LH, et al