Compounded medications are legally permitted in certain circumstances, typically when a patient has a specific medical need that can't be met by commercially available products, or during drug shortages
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Therefore, the GLP-1-induced excitation of MCs, probably via inhibition of voltage-dependent potassium channel conductance and enhancement of glutamatergic neurotransmission, could lead to changed excitability of higher olfactory cortical as well as hypothalamic regions to change metabolic states
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