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After inserting the needle completely, press the injection button and hold for the duration specified in your product's instructionsthis varies significantly (approximately 6 seconds for Ozempic, 10 seconds for Wegovy, until you hear the second click for Trulicity)

Cancer Res 2013

Bordini et al

They also noted flaws in the literature: the Morosil and Eriomin studies did not show significant weight loss in the active groups, and the study for Supresa also showed only minimal weight loss