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3.2.1 Neuroinflammatory imaging in amyotrophic lateral sclerosis In SOD1G93A transgenic mice, [18F]DPA714 uptake in skeletal muscle rises significantly at presymptomatic stages, reflecting upregulated TSPO in myocytes independent of leukocyte infiltration

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A 2021 trial (SURPASS-1) showed that 92% of people with type 2 diabetes on tirzepatide lowered their HbA1c levels to less than 7% (compared to 19% for those on placebo)