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Methods: In this study, Mendelian randomization (MR) analysis, primarily inverse-variance weighted MR, was used to assess the causal effect of six endogenous and five exogenous diet-derived antioxidants on the risk of six cancers

Administration of AdipoRon, an adiponectin receptor activator, mitigates tubule injury in db/db mice by enhancing lipophagy and suppressing ectopic lipid deposition and oxidative stress in TECs (85)

89% of adults taking Wegovy HD lost 5% or more of their body weight in a separate clinical study

But it's increasingly being used off-label for weight loss by otherwise healthy people here and especially in the United States