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Another, evaluating the highest-quality trials specifically, concluded glutathione "is not beneficial enough as a skin-whitening agent," since it only worked on some parts of the body and the effect didn't last
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Together, they bind to specific regions of DNA called antioxidant response elements (AREs), which are located in the promoter or enhancer regions of NRF2 target genes
However, quality of life assessments in clinical trials may not capture subtle mood changes or emotional experiences that individual patients might notice in real-world use
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