Subcutaneous protocols start at 0.25 mg weekly for four weeks and titrate every four weeks (0.5 1 1.7 2.4 mg) to a maintenance dose
This study was supported by NIH grants R01 DK116004 (GL) and R01 DK094871 (GL), start-up funds (GL), American Heart Association (AHA) postdoctoral fellowship 23POST1026084 (AS), Biotechnology and Biological Sciences Research Council grant BB/M020991/1 (SCS), and New Life Foundation grant 14-15/20 (SCS)
361,362,363,364,365 Current research is increasingly focused on early-stage treatments
These include improved blood sugar control, lower cholesterol levels, and reduced risk of heart disease
In other words, researchers are still sorting out how much of the anti-inflammatory effect is direct and how much is downstream from metabolic improvement