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Messing, A

A smaller number sit in a short resting phase

Indeed, 4-en-VPA is transformed through -oxidation to reactive intermediates such as 2-propyl-2, 4-pentadienoic acid (2, 4-dien-VPA) that are capable of depleting mitochondrial GSH, as suggested by rat studies [60]

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Ferroptosis in hepatocellular carcinoma can be promoted, resulting in two or three times more cell death, by sorafenib treatment combining with Rb knockdown using RNA interference (Louandre et al., 2015)