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These drugs offer dual benefits, improving glycemic control while boosting weight loss, which makes them a preferred option in managing both type 2 diabetes and obesity

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doi: 10.1016/j.tem.2016.03.017 81 SlleyEKunSSzijrtIAKertszMWittmannIMolnrGA

This hypothetical mechanism with deeper desensitization of KARs compared to AMPARs is consistent with slower recovery from desensitization observed in KARs compared to AMPARs (Gangwar et al., 2024b