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Blood 129 , 27192726 (2017)

This dual action provides several benefits: Enhanced insulin secretion when blood sugar is elevated Suppressed glucagon release to reduce liver glucose production Slowed gastric emptying leading to increased satiety Improved fat metabolism through GIP receptor activation Better insulin sensitivity in peripheral tissues The unique aspect of tirzepatide is its imbalanced design it has a stronger affinity for GIP receptors than GLP-1 receptors, which may contribute to its enhanced efficacy while potentially minimizing certain side effects

Moreover, our systematic review extends beyond the scope of another recent network meta-analysis, which, while including s.c

5a, treatment with G/D-CuP elevated the number of Ki67-positive cells