10.1007/s10142-014-0379-y 96 LieberherrD.WagnerU.DubuisP
A., and Driscoll, D
The GSH transport between the various cell compartments is vital to buffer reactive oxygen species (ROS) and facilitate redox signaling in order to control cell growth, development and defense, as well as regulate cell proliferation
Key research themes involving glutathione include: Scavenging of free radicals (e.g., peroxides, nitrogen dioxide, hypochlorous acid) Support of other antioxidant systems (e.g., vitamin C and vitamin E recycling) Detoxification via glutathione S-transferases and related enzymes Regulation of protein folding, disulfide-bond formation, and thiol redox status Modulation of inflammatory mediators, nitric oxide pathways, and cellular metabolism Because endogenous glutathione synthesis capacity appears to decrease with age in many models, glutathione is frequently used as both an experimental variable and a biomarker in studies of aging, disease susceptibility, and redox imbalance
If needed, attempt a second bathroom visit during the afternoon motility window (2 hours after lunch)