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Ferroptosis in drug resistance in cancer Despite significant advances in cancer treatment, drug resistance remains a major clinical challenge
Dysfunctional mitochondria in neutrophils, macrophages, and T lymphocytes alter cytokine production, phagocytic activity, and antigen presentation, tipping the balance toward excessive inflammation or postoperative immunosuppression, thereby exacerbating organ injury
Led by MIT graduate Dr
Alois Alzheimers original descriptions of extracellular plaques in the late 19th century [530]
SIRT1 also inactivates p53 which is involved in neuronal cell death (Kim et al
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