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The -synuclein aggregates specifically bind to the translocase of outer mitochondrial membrane (TOMM) 20, significantly inhibiting the transmembrane transport of mitochondrial precursor proteins, ultimately leading to mitochondrial dysfunction in dopaminergic neurons [96]
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10.1371/journal.pone.0301867 PLoS One 7 BochevaG.BakalovD.IlievP.Tafradjiiska-HadjiolovaR
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