10.1016/j.theriogenology.2004.01.011
The molecular signaling that controls these phases involves intricate cascades of growth factors, transcription factors, and structural proteins
However, the role of nutritional supplements in CIPN remains controversial due to the varied mechanisms of neuropathy induced by different antineoplastic drugs and the presence of complex drug interactions, and further research on such drugs is necessary in the future
In ovarian cancer cell lines A2780 and SKOV-3, Agrimonolide not only restricts proliferation, migration, and invasion in a dose-dependent manner but also initiates apoptosis
Conversely, for basic peptides (net positive, rich in Lys/Arg), using a slightly acidic solvent like 510% acetic acid can protonate those residues and enhance solubility4