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demonstrated that under hypoxic conditions, lipid droplet (LD) accumulation results primarily from FABP3/7-mediated fatty acid uptake, while de novo lipogenesis is downregulated
Efficiently clearing out the previous month's hormones is a vital part of this reset
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This strategy is the basis for many anticancer therapeutics, including chemotherapeutics, radiotherapies, and most small-molecule inhibitor-based therapies, which impair tumor metabolism and induce excessive ROS accumulation, inducing cell toxicity and death
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