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Furthermore, the STEP 3 trial demonstrated that combining the medication with intensive behavioral therapy and a low-calorie diet resulted in a 16.0 percent reduction at week 68 (Source: STEP 3 Trial, Wadden et al., JAMA 2021)

Growing understanding about the chronic nature of obesity indicates long-term management is necessary for patients to maintain their weight loss

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Loren Pickart's deep involvement with GHK-Cu (from discovery through commercialisation) gives him unique expertise but also represents a potential conflict of interest

The reason for this is that multiple trials have shown that the bioavailability of SC MTX is greater, and the bioavailability of oral MTX is somewhat variable