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increased survival in the TAC model

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A careful sequence alignment of SsCm1 and other Cms showed that SsCm1 has obvious differentiation in several reported essential amino acids for enzyme activity, such as A93 and V149 of SsCm1 are K and T respectively in the Cms with enzyme function, and also showed differences in many conserved amino acids 39,43

Pinheiro S, Carvalho R, Ramos S, Diogo C, Caetano M, Cabral L, Cruzeiro C (2013) Toxic epidermal necrolysis: the experience of Coimbras burn unit

Objetivo primario (MACE): HR 0,86 (IC95% 0,77-0,96