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Puca F, Bricolo A, Turella G

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A deeper understanding of how choline-derived metabolites influence innate immune signaling may uncover new therapeutic targets and biomarkers for inflammatory disease management and precision immunomodulation

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As emphasized by Kaufmans lab concerning the clinical utility of oral GABA, there is evidence that the GABAA receptor EC 50 is of low affinity (50-400 M) (55)

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Off-label prescribing is legal in the United States, but it carries specific risks when no pediatric pharmacokinetic or efficacy data exist

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Tirzepatide, without glucagon agonism, does not carry that specific signal

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