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Infants born prematurely have immature liver function and cannot oxidize benzyl alcohol to benzoic acid and subsequently conjugate it to hippuric acid
This gives the kojic acid time to penetrate and work its magic
125127 When pyruvate kinase is deficient or dysfunctional, there is an increased reliance on alternative pathways for energy production leading to increased breakdown of ATP and subsequent accumulation of adenosine monophosphate
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Journal of Experimental Pharmacology (2012)
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