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Third, have you filed continuation and divisional applications on the method-of-use claims for the indications you are not actively pursuing clinically

Thrombocytopenia is what limits the rival senolytic ABT-263/navitoclax

He noted that the three pillars of an FDA finding of safe and effective include demonstrating clinical efficacy, validating the manufacturing process and completing the required toxicology studies

The patents held by the manufacturers, Novo Nordisk (for Ozempic and Wegovy) and Eli Lilly (for Mounjaro and Zepbound), prevent other companies from producing generic equivalents for several more years

312.2(b)(3) and 312.160 , under Part 312 of Title 21 of the Code of Federal Regulations