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Similar considerations may limit the utility of the injectable agents, tirzepatide (dual GLP-1 and glucose-dependent insulinotropic polypeptide [GIP] agonist), and retatrutide (triple glucagon, GIP, and GLP-1 receptor agonist)
"Efficacy and tolerability of tirzepatide, a dual glucose-dependent insulinotropic peptide and glucagon-like peptide-1 receptor agonist in patients with type 2 diabetes: A 12-week, randomized, double-blind, placebo-controlled study to evaluate different dose-escalation regimens"
Backhed F, Ding H, Wang T, Hooper LV, Koh GY, Nagy A, et al
Kannengiesser et al
Decreases inflammation in the small and large intestines
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