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When estrogens were first studied, it was observed they caused maturation of the vaginal mucus membrane in a way analogous to estrogens action on the skin
Further Reading References: (1) Laferrre B, Abraham C, Russell CD, Bowers CY
They further suggest that the ability of these gut-brain peptides to reduce alcohol drinking possibly involves an attenuated alcohol reward
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They found that in addition to slowing the progression of degeneration in the treatment group compared to controls, the peptide also improved levels of the protein aggrecan
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