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Additional contributing factors include: Prolonged gastric distension due to delayed emptying Changes in gastric motility patterns Individual anatomical variations, such as hiatus hernia Concurrent use of other medications that affect gastric function It is worth noting that obesity itself is a significant risk factor for GORD, as excess abdominal adiposity increases intra-abdominal pressure

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Divide the usable area into quadrants: upper right, upper left, lower right, lower left