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Should GLP-1 patches complete clinical development and receive regulatory approval in future, they would undergo health technology assessment by NICE to determine cost-effectiveness and appropriate positioning within NHS treatment pathways

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Notably, the inverse correlation between sarcosine/serine levels and cognitive dysfunction/depression suggests that sarcosine/serine supplementations might have therapeutic applications in LC patients

The most realistic near-term path to expanded coverage is Scenario 2 (sleep apnea indication)

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