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During an acute infection, such as with the SARS-CoV-2 virus, the immune system mounts a massive inflammatory response to neutralize the pathogen
That being said, there are other aspects of the medications that seem to have other effects that are independent of weight loss, independent of blood glucose lowering, that I do not think we still fully have an answer to, he said
& Donnelly, J
Variability-accommodating pharmacodynamics (time-integrated effects): When pharmacodynamic effects integrate over time and depend on the area under the curve (AUC) or sustained receptor occupancy rather than peak concentration, transient fluctuations in plasma concentration have limited clinical consequences
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