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With specific effects on infiltrating macrophages in streptozotocin-induced diabetes, exendin-4 attenuated adverse cardiac remodeling
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(Pedraza et al., 2010)
Inhibition of incretins by DPP-4 inhibitors prolongs the half-life of incretins (GLP-1 & GIP) and is associated with increased insulin release & reduced glucagon release
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