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Studies conducted on rat -cells (47) and cell lines expressing recombinant GLP-1R and GIP-R in vitro and human islets (41) demonstrated that the adenylate cyclase was influenced by signals arising from the stimulation of both receptors, mainly deriving from GIP ( Figure 1 )
Stehouwer CDA, Gall MA, Hougaard P, Jakobs C, and Parving HH (1999)
GLP-1 medications lower inflammation, improve blood vessel function, and support healthy blood pressure and cholesterol levels
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