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Ozempic pens can be stored at room temperature (59F to 86F or 15C to 30C) or in a refrigerator (36F to 46F or 2C to 8C), away from direct sunlight, for up to 56 days

Some individuals report increased aggression or irritability, though this appears dose-dependent and individual

In August 2025 , the FDA approved Wegovy for another use: to treat a type of fatty liver disease called metabolic dysfunction-associated steatohepatitis (MASH) in adults who have moderate to advanced liver scarring (fibrosis) but do not have permanent liver damage (cirrhosis)

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Microbial tryptophan metabolism involves multiple metabolites (Fig