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And nausea, while the most common, is seldom what ends treatment: permanent discontinuation due to a gastrointestinal reaction occurred in 4.3% of treated patients versus 0.7% on placebo, and specifically due to nausea in 1.8% versus 0.2%

Weight loss may slow slightly from the pace of months 2 through 4, but cumulative results continue to compound

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[1] For those on oral therapy, a repeat B12 level may be checked after several months to confirm response

The preservative prevents new growth but cannot eliminate bacteria already introduced through puncture events