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Perraudeau et al 2020 doi: 10.1136/bmjdrc-2020-001319 About Pendulum Therapeutics Pendulum Therapeutics is a biotechnology company pioneering next-generation microbiome innovations designed to improve human health

Concurrently, calcium transfer is structurally embedded into ERMCS via the inositol 1,4,5-trisphosphate receptor (IP3R)-glucose-regulated protein 75 (GRP75)-voltage-dependent anion channel (VDAC) axis, which funnels ER-released Ca2+ across the outer mitochondrial membrane (41,42)

Desprs, J.-P., Golay, A

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The ESSENCE trial (NCT04822181) enrolled 1,197 adults with biopsy-proven MASH and moderate to advanced liver fibrosis (Stage F2 to F3)