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(PubMed) Neumann WL, Coss E, Rugge M, Genta RM
Some people may also experience adverse effects like mild diarrhea, itching, or a swelling sensation in the body
One of the most notable studies in this field, often referred to as the "Tomato Pill" trial, was a randomized, double-blind, placebo-controlled study that measured the direct vascular effects of lycopene on patients with established cardiovascular disease
History [edit] Descriptions of deficiency effects [edit] Between 1849 and 1887, Thomas Addison described a case of pernicious anemia, William Osler and William Gardner first described a case of neuropathy, Hayem described large red cells in the peripheral blood in this condition, which he called "giant blood corpuscles" (now called macrocytes), Paul Ehrlich identified megaloblasts in the bone marrow, and Ludwig Lichtheim described a case of myelopathy