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Ferrostatin-1 and Liproxstatin-1, two well-known inhibitors of ferroptosis, for instance, have demonstrated protective benefits in both ARDS and ALI models ( 3.2 Endothelial cell dysfunction One characteristic of ARDS is endothelial cell dysfunction, which exacerbates lung injury by disrupting the alveolar-capillary barrier

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Colon-targeted KPV study Demonstrated that oral, colon-specific KPV therapy effectively reduced inflammation in preclinical models of inflammatory bowel disease