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Lowering blood glucose levels is the basis of diabetes treatment, not only in terms of preventing microvascular complications, including CKD, but also in preventing cardiovascular events
Both GLP1-RAs and SGLT2is contribute to weight loss through different mechanisms
2014 Feb;28(2):514-9
Published data from the Phase 3b STRIDE trial reported that Ozempic 1 mg via SC injection once weekly improved maximum walking distance by 13% relative to placebo after 52 weeks
3.1.2 Semaglutide: mechanistic endpoints and effect amplification in combination therapy Evidence for semaglutide tends to focus on mechanistic and tissue-distribution endpoints
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