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Still, this mechanism was discovered in the 1980s - it took us 40 years to get here
Circulation 2008;117:23402350
For example, ER stress can promote acinar cell apoptosis by activating the p53/AIFM2 axis and the PERKJNK pathway, 252,253,254,264 induce caspase-1-dependent pyroptosis via activation of the PERK pathway, 265 and trigger necroptosis in pancreatic acinar cells by enhancing CTSB maturation and activating the PKCJNKc-Jun cascade
In contrast to mitochondrial -oxidation, incomplete peroxisomal oxidation of fatty acids yields acetyl-CoA and shortened medium-chain acyl-CoAs
Probably owing to the high flexibility of DII, some of its features are not well resolved
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