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In one landmark trial, adults without diabetes who took the highest weekly dose lost an average of 20.9 percent of their body weight over 72 weeks, compared with 3.1 percent on placebo, and more than half reached at least a 20 percent reduction (SURMOUNT-1 trial, New England Journal of Medicine, 2022)

A cross-sectional study by Glabska et al

Understanding your options and what to expect Delivery timing and how the process works General questions before you decide Current Evidence on Ozempic and Bone Density The relationship between Ozempic and bone density remains an area of ongoing research, with current evidence suggesting no signal of increased fracture risk in most patients

The glucagon effect shifts toward increased energy expenditure and fat oxidation rather than simply elevating glucose