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J Clin Endocrinol Metab, 2001
Use of phosphate-based fertilizers which contain arsenic, cadmium, lead in trace amount, use of untreated sewage that contained the heavy metals as fertilizers, contaminated run-off from mining and smelting industries near agricultural farmlands, industrial wastes from manufacturing industries that leach into the soil, urban construction also introduce heavy metals to the soil, chemical spills, landfill leakage, recycling of materials, atmospheric deposition, weathering and erosion as well as other natural processes (Adamu et al
Metabolomic pathway analysis demonstrated that these metabolites are involved in sulfurate amino acids metabolism, with respect to cysteine, and glutathione synthesis (Fig
They are the right choice for patients whose primary goal is total body weight reduction and who need pharmacological support for appetite management
PMCID: PMC5750484
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