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Vitamin B12, on the other hand, plays a crucial role in the synthesis of DNA, red blood cells, and the maintenance of the nervous system

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sleep issues are often secondary to something else

This results in B12 malabsorption, deficiency, and megaloblastic (abnormally large and dysfunctional) RBCs in many cases

Baseline vitamin B12 levels before starting metformin Annual monitoring for patients on long-term metformin therapy Consideration of vitamin B12 supplementation if deficiency is detected Antibiotics and Chemotherapy Agents That Affect B12 Metabolism Certain antibiotics and chemotherapy agents can harm vitamin B12 metabolism