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-Ketoglutarate (-KG), a TCA cycle intermediate, serves as an essential cofactor for TET and JmjC demethylases, facilitating DNA and histone demethylation [251]

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It may interfere with chemotherapy drugs or decrease the efficacy of certain antipsychotics

For weight loss, the injections are approved for people with a BMI of 27 and above, and weight loss surgery is approved for a BMI of 30 and above, though its more common among people with with a BMI over 35

Selective mitochondrial glutathione depletion by ethanol enhances acetaminophen toxicity in rat liver