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Hypertension 61 , 513 (2013)
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In the study, participants with a responsive genetic score had an 82% increase in the likelihood of acheiving weight loss with a GLP-1 medication.[ref] Another study showed that GLP1 receptor variants are associated with greater weight loss on GLP-1 RA drugs.[ref] Common genetic variants in the GLP1R (GLP-1 receptor) gene impact weight and type 2 diabetes risk
Comparison with other studies Overall, events of suicidal ideation and self-harm have not been found to be imbalanced in clinical trials between randomised groups.67 However, these trials were limited by their sample sizes and thus could not detect these rare but potentially important adverse events
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