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Endocrinology (1993) 133:5762

It is well-known that the gut metabolite sodium butyrate (NaB) could promote GLP-1 secretion from intestinal L cells

The culture medium was then replaced with 30 M M-CuP solution, 15 M D-CuP solution, or hydrogel extract at 37 C for another 24 h

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Conclusion GLP1 medications, particularly tirzepatide, have emerged as a powerful tool for improving obstructive sleep apnea, with the SURMOUNT-OSA trial demonstrating AHI reductions of 50 to 60 percent at one year

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