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For some patients, the body might react to the changes brought about by this process, resulting in inflammation and, consequently, discomfort or pain in the joints
By providing multiple prebiotic sources, ImproBiome supports a more diverse and resilient gut environment capable of maintaining comfort even when digestive patterns change
Extended interruptions may warrant restarting at a lower dose to minimize gastrointestinal side effects, particularly if the patient had previously experienced significant nausea or vomiting during dose escalation
An overall summary of the LEADER risk score model, including the interactions considered in it, are outlined in Additional file 1: Appendix Table S1
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