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Biochem Biophys Res Commun, 2011

This metabolic shift converts an initially heterogeneous and largely cell-autonomous response into uniform collective necrosis accompanied by extensive lysosome rupture and wave-like multicellular propagation

It initially gained attention in gastrointestinal research, but over time it has been studied for potential roles in musculoskeletal recovery contexts, including tendon irritation, ligament strain, and general connective tissue support

Complete loss of expression of H3K27me3 was observed in 72% of malignant peripheral nerve sheath tumors compared with 37% of loss found in melanomas, including primary desmoplastic/fusiform cell melanomas, indicating that complete loss of H3K27me3 is not specific for malignant peripheral nerve sheath tumor in the differential diagnosis, especially with desmoplastic/fusiform cell melanomas

Oxalobacter formigenes , bacteria found in the digestive tract, prevented calcium oxalate kidney stones in clinical studies