High doses of Vitamin B12 are used to quickly fill up the bodys stores
It works by reducing the activity of tyrosinase, an enzyme involved in the production of melanin, and by minimizing the appearance of discolored skin patches
However, sustained high doses, overdose, fasting, alcohol use, or pre-existing liver disease can overwhelm glutathione reserves, increasing risk of hepatotoxicity and oxidative stress
21 , 30633074, doi: 10.1096/fj.07-8166com (2007)
The myristoylated FSP1 can be recruited into the plasma membrane, inhibiting ferroptosis through the antioxidant effect of CoQ10, generating a lipophilic radical trapping antioxidant (RTA) that halts the propagation of lipid peroxides [23]