Definitions of the inclusion/exclusion criteria were based on diagnostic codes (i.e., International Classification of Disease [ICD] version 9 and 10) in the problem list, one inpatient encounter, at least two outpatient encounters within two years, or one procedure code which were provided in the supplement (eTable 1)
In the fed state, postprandial metabolism is essentially characterized by high insulin levels that are responsible for antilipolytic action (e.g., by inhibiting HSL) and antigluconeogenic action (by suppressing this metabolic pathway) as well as for lipogenic action (e.g., by stimulating LPL) [87,117]
While our standard programs focus primarily on weight loss, Proactive Health is designed for proactive health optimization
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The authors are thankful to the Deanship of Graduate Studies and Scientific Research at the University of Bisha for supporting this work through the Fast-Track Research Support Program