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Similarly, a nationwide retrospective cohort study of 1,221,218 patients with diabetes demonstrated a reduced risk of colorectal cancer with GLP-1RA use over a 15-year follow-up period (Wang et al., 2024b)

The findings suggest that GLP-1 medications may act on a shared biological pathway underlying multiple forms of addiction

GLP-1 is a glucose-dependent intestinal hypoglycemic polypeptide hormone secreted by L cells of the terminal jejunum, ileum and colon

Splitting the dose across two weeks would create unpredictable hormone fluctuations, potentially leading to inconsistent appetite suppression, metabolic dysregulation, or unnecessary side effects

This assesses your overall health, current medications, known allergies, liver function indicators, and specific skin concerns