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10.1097/BOR.0b013e32835d951e 19 ChenD.FanJ.WangP.ZhuL.JinY.PengY.et al (2012)
TMAO levels also rise as kidney function degrades, which correlates with mortality in CKD patients [12]
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These diseases are typically characterized by persistent inflammatory responses and tissue damage, and their onset and progression involve the combined effects of genetic susceptibility, environmental factors, and dysregulated immune regulation ( Macrophages exhibit marked functional plasticity, and their phenotypes can dynamically change in response to microenvironmental signals
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