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Book Review Therapeutic Drugs Edited by Sir Colin Dollery
Ramot, Y
This intermittent use pattern, while not extensively studied, may provide a practical approach for individuals who cannot afford or tolerate continuous long term treatment
Merck has pursued a standard biologic lifecycle strategy: filing additional method-of-use patents covering each new approved indication, formulation patents covering the 200 mg/3 mL concentration, and combination therapy patents covering pembrolizumab plus specific chemotherapy regimens
Starting with a low dose and increasing gradually can help minimize discomfort
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